Aetiological Agent of Enterically Transmitted Non-A, Non-B Hepatitis

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Aetiological agent of enterically transmitted non-A, non-B hepatitis.

Virus-like particles (VLPs) with a mean diameter of 32 nm were recovered from the stools of three acute phase cases of enterically transmitted non-A, non-B hepatitis (ET-NANBH) occurring in the Soviet Union, North Africa and North America. VLPs from two of these cases were studied in detail and were shown to react specifically with antibody in acute phase sera obtained from other cases of ET-NA...

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Hepatitis E virus (HEV), the major etiologic agent of enterically transmitted non-A,

● Hepatitis E virus (HEV) is ubiquitous in U.S. swine herds, but does not cause clinical illness in swine. ● Hepatitis E is a zoonotic disease risk and cross-species infection occurs. In 2003 in Japan, the first direct evidence of zoonotic transmission of HEV was documented in two outbreaks involving human consumption of raw wild boar liver and raw deer meat; one patient died. ● Xenotransplanta...

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Seroepidemiology of water-borne hepatitis in India and evidence for a third enterically-transmitted hepatitis agent.

Many epidemics of water-borne hepatitis have occurred throughout India. These were thought to be epidemics of hepatitis A until 1980, when evidence for an enterically transmitted non-A, non-B hepatitis was first reported. Subsequently, hepatitis E virus was discovered and most recent epidemics of enterically transmitted non-A, non-B hepatitis have been attributed to hepatitis E virus infection....

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Enterically transmitted non-A, non-B hepatitis: serial passage of disease in cynomolgus macaques and tamarins and recovery of disease-associated 27- to 34-nm viruslike particles.

An experimental model of enterically transmitted non-A, non-B hepatitis (ET-NANBH) was established in tamarins (Saguinus mystax mystax) and cynomolgus macaques (Macaca fascicularis). First-passage animals were inoculated with two different stool suspensions obtained from human patients with well-defined ET-NANBH that originated from Burma and Pakistan, where epidemics of ET-NANBH occur. Both in...

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Etiology of enterically-transmitted hepatitis among foreigners in Nepal.

We report the etiology of hepatitis in travelers over a ten year period from January 1994 December 2003. Clinics catering to expatriates and tourists in endemic Nepal provided sera for diagnostic testing from persons with signs and symptoms compatible with clinical hepatitis and alanine transaminase levels 2 1/2 times greater than normal. Hepatitis E was determined with anti-HEV IgM, and HEV RT...

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ژورنال

عنوان ژورنال: Journal of General Virology

سال: 1988

ISSN: 0022-1317,1465-2099

DOI: 10.1099/0022-1317-69-3-731